Clinical Efficacy of Acupuncture Treatment in Combination With RehaCom Cognitive Training for Improving Cognitive Function in Stroke: A 2 x 2 Factorial Design Randomized Controlled Trial
发布日期
2016-12-1作者
Jiang, C (Jiang, Cai)
Yang, SL (Yang, Shanli)
Tao, J (Tao, Jing)
Huang, J (Huang, Jia)
Li, YY (Li, Yinyan)]
Ye, HC (Ye, Haicheng)
Chen, SJ (Chen, Shanjia)
Hong, WJ (Hong, Wenjun)
Chen, LD (Chen, Lidian)
所在专题
摘要
Objective: The aim of this study was to identify the clinical efficacy of acupuncture in combination with RehaCom cognitive training in poststroke patients with cognitive dysfunction.
Methods/Design: This study was a 2 x 2 factorial design randomized controlled trial comparing acupuncture, computer-assisted cognitive rehabilitation, and the usual treatment by per-protocol analysis. The trial was completed by 204 stroke patients, including 49 patients in a control group, 52 patients in an acupuncture treatment group, 51 patients in a RehaCom training group, and 52 patients in an acupuncture combined with RehaCom group. All of the patients accepted basic treatment and health education. The interventions continued for 12 weeks (30 minutes per day, 5 days per week). The relative cognitive and functional outcomes were measured at baseline and 12 weeks (at the end of intervention) using the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), and Functional Independence Measure (FIM) scales.
Results: After 12 weeks of treatment, the functional statuses of the patients in each of the 4 groups showed varying degrees of improvement. Multiple comparisons of the changes in the MMSE, MoCA, and FIM scores indicated that acupuncture combined with RehaCom cognitive training (ACR) had enhanced therapeutic effects on the functional statuses of the stroke patients (P < .05). In addition, ACR had similar therapeutic effects on the functional statuses of the stroke patients according to each of the assessment scales applied (P Delta(change) (value) MMSE = 0.399, P Delta MoCA = 0.794, P Delta FIM = 0.862). The interaction effect values between acupuncture and RehaCom training (acceptance or nonacceptance) were as follows: Delta MMSE: F = 6.251, P = .013; Delta MoCA: F = 4.991, P = .027; and Delta FIM: F = 6.317, P = .013. Further, the main effect values for acupuncture and RehaCom training were both significant (P < .05).
Conclusions: There is an interaction effect in the treatment of stroke patients using ACR. The use of acupuncture in combination with RehaCom training has better therapeutic effects on the functional statuses of poststroke patients than the use of either treatment alone, demonstrating the clinical significance of this combination therapy. (C) 2016 AMDA - The Society for Post-Acute and Long-Term Care Medicine.
描述
通讯作者地址: Chen, LD (通讯作者) Fujian Univ Tradit Chinese Med, 1 Qiuyang R, Fuzhou 350108, Fujian, Peoples R China.地址: [ 1 ] Fujian Univ Tradit Chinese Med, 1 Qiuyang R, Fuzhou 350108, Fujian, Peoples R China
[ 2 ] Fujian Univ Tradit Chinese Med, Rehabil Hosp, Dept Rehabil Med, Fuzhou, Fujian, Peoples R China
[ 3 ] Fujian Med Univ, Hosp Quanzhou 1, Dept Rehabil Med, Quanzhou, Peoples R China
电子邮件地址:lidianchen1987@126.com